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Computed Tomography (CT) Scan of the Knee with Intravenous Contrast

Published: August 9, 2026Updated: August 16, 2026

A CT scan uses X-rays and IV contrast to create detailed images of the knee, including the bones, cartilage, and surrounding soft tissues.

Quick summary

["This imaging test can help identify injuries and structural changes in the knee that may not be clearly visible on plain X-rays."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36222-8
Short code
CT Knee W contr IV
Synonyms
CT Knee W contr IV
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A CT scan of the knee uses X-rays taken from different angles to create detailed cross-sectional images. Intravenous contrast, given through a vein, may help improve the visibility of certain tissues and abnormalities.

Why might I need this test?

Your clinician may order this test to evaluate a knee injury, persistent pain, swelling, or difficulty walking. It can provide detailed information about fractures, cartilage and bone changes, infection, or other abnormalities.

How is the test performed?

You will lie on a table that moves through a CT scanner while X-ray images are taken. If contrast is required, it is usually injected into a vein in your arm before the scan and may cause a brief warm or flushing sensation.

How do I prepare for the test?

Follow your clinician's instructions, and tell the imaging staff if you have previously had a serious reaction to contrast, have kidney disease, are pregnant or may be pregnant, or take medicines such as metformin. Remove metal objects and follow the facility's instructions for clothing and movement during the scan.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal findings may include fractures, cartilage or bone changes, joint narrowing, fluid collections, infection-related changes, or masses. The scan should be interpreted alongside your symptoms, physical examination, and other imaging or laboratory tests because some findings may have more than one cause.

Short name

CT knee with IV contrast

Frequently asked questions

Is a CT scan of the knee the same as an X-ray?
No. A CT scan uses multiple X-ray images to create detailed cross-sectional pictures, which can show complex bone, cartilage, and soft-tissue changes more clearly.
Does IV contrast always cause side effects?
Most people tolerate IV contrast well. Mild effects can include a warm or flushing sensation, while allergic-like reactions and kidney-related problems are uncommon but can occur.
Will the scan diagnose the cause of my knee pain?
The scan may identify structural abnormalities that help explain the pain, but your clinician will interpret the images together with your history, examination, and any other tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy