Skip to content

Total bilirubin (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of bilirubin in your blood, a yellow pigment produced when your body breaks down old red blood cells. It helps assess liver function and detect conditions like jaundice, bile duct blockages, or hemolytic anemia.

Quick summary

["Bilirubin levels can signal liver or blood disorders and help guide treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24814-6
Short code
CT Liver
Synonyms
CT Liver
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for liver problems, such as hepatitis, cirrhosis, or bile duct issues. It’s also used to monitor conditions like Gilbert’s syndrome or hemolytic anemia, or to evaluate jaundice in newborns or adults. Sometimes, it’s part of a routine check-up if you have symptoms like yellowing skin or dark urine.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a liver function panel. Bring any medications you’re taking, as they can sometimes affect results. If you’re pregnant, breastfeeding, or have recent blood transfusions, let your provider know.

What Happens During the Test?

A small needle is inserted into your arm to draw blood. The process takes about 5 minutes, and you may feel a brief pinch. The blood is sent to a lab for analysis. If you’re tested for newborn jaundice, a heel prick is used instead.

What Do Results Mean?

Results are compared to standard ranges, but exact values depend on the lab. High bilirubin levels (hyperbilirubinemia) may indicate liver disease, gallbladder issues, or red blood cell breakdown. Low levels are less common but could signal liver problems or certain medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Bilirubin

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab and whether it’s part of a larger panel.
Can I eat or drink before this test?
If fasting is required (common for liver panels), avoid food for 8–12 hours before testing. Water is usually allowed unless otherwise instructed. If fasting isn’t needed, you can eat normally.
Does this test hurt?
The blood draw itself causes a minor pinch, but most people describe it as brief and manageable. If you’re nervous, let your provider know—they may offer a numbing cream or distraction techniques.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy