Total Serum Protein (with Electrophoresis Separation)
This test measures the overall protein content in your blood and breaks down the different types of proteins (such as albumin and globulins) using an electrophoresis method.
["Helps assess protein balance and identify potential imbalances in blood proteins."]
Key facts at a glance
- LOINC
- 37232-6
- Short code
- CT LSJ
- Synonyms
- CT LSJ
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ct
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors may order a serum protein profile to diagnose conditions like kidney disease, liver problems, infections, or certain cancers. It can also help evaluate nutritional status or monitor treatment responses for conditions affecting protein levels.
Types of Proteins Measured
The test typically includes measurements for albumin, globulins, and total protein. Albumin helps maintain fluid balance, while globulins support immune function. Abnormal levels may indicate underlying health issues.
Sample Preparation and Collection
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum (the liquid part after clotting). This serum is analyzed using electrophoresis to separate proteins by size and charge.
Possible Results and Interpretation
Results are often reported as a breakdown of protein fractions (e.g., albumin, alpha, beta, gamma globulins) alongside total protein levels. Abnormal patterns may signal conditions like hypoalbuminemia (low albumin), hyperglobulinemia (high globulins), or protein-losing syndromes.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Low total protein or specific protein imbalances may indicate malnutrition, chronic kidney disease, liver dysfunction, or inflammatory conditions. High globulin levels could suggest immune disorders or chronic infections, while low albumin may reflect poor nutritional status or organ failure.
Short name
Serum protein profile
Frequently asked questions
What Does a High or Low Protein Level Mean?
How Often Should I Get This Test?
Can Diet Affect My Protein Test Results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy