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Computed Tomography (CT) Scan of the Mediastinum with Intravenous Contrast

Published: August 9, 2026Updated: August 17, 2026

A CT scan of the central chest area using contrast injected through a vein to examine the mediastinum, nearby blood vessels, lymph nodes, and other structures.

Quick summary

["This imaging test uses CT scans and injected contrast to evaluate the central chest and nearby structures in greater detail."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
87874-4
Short code
CT Mediastinum W contr IV
Synonyms
CT Mediastinum W contr IV
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A mediastinal CT scan is an X-ray–based imaging test of the mediastinum, the central area of the chest between the lungs. Intravenous contrast is injected through a vein to help highlight blood vessels, organs, lymph nodes, and abnormalities.

Why might I need this test?

Your clinician may order this test to investigate symptoms such as chest pain, coughing, shortness of breath, or unexplained weight loss. It may help identify problems involving lymph nodes, blood vessels, the heart, the esophagus, or nearby tissues.

How is the test performed?

You will lie on a scanning table while a CT machine takes several images. A nurse or technologist will usually place an IV line in your arm and inject the contrast, then you may be asked to remain still or briefly hold your breath.

How do I prepare for the test?

Follow your imaging center’s instructions about eating, drinking, and medications. Tell the care team about any contrast allergy, kidney disease, pregnancy, or medicines such as metformin, because these may affect the plan or whether contrast can be used.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Mediastinal CT with IV contrast

Frequently asked questions

Does this CT scan use radiation?
Yes. CT scans use a small amount of ionizing radiation, and intravenous contrast adds detailed information about blood vessels and tissues.
Is intravenous contrast different from the oral contrast used for some CT scans?
Yes. Intravenous contrast is injected into a vein and circulates through the bloodstream. Some CT scans may also use oral contrast, but this test specifically refers to the intravenous form.
What should I do if I have had a reaction to contrast?
Tell the imaging center before the appointment. Previous reactions, along with any kidney problems or other relevant conditions, may affect how the contrast is given or whether a different test is recommended.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy