Skip to content

Genetic analysis of nucleic acid probe for cystic fibrosis-related mutations (CFTR gene)

Published: August 9, 2026Updated: August 16, 2026

This test checks for specific genetic changes linked to cystic fibrosis, a condition affecting the lungs and digestive system.

Quick summary

["Helps determine if you may carry mutations associated with cystic fibrosis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92684-0
Short code
CT + NG + TV DNA Pnl Ur NAA+probe
Synonyms
CT + NG + TV DNA Pnl Ur NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may recommend this test if you have symptoms of cystic fibrosis, a family history of the condition, or if you’re planning pregnancy and have a higher risk of passing cystic fibrosis genes to your child. It can also be used for newborn screening in some cases.

How the Test Works

This test is not a diagnostic test for cystic fibrosis itself but identifies whether certain genetic mutations are present, which can influence further medical decisions.

What to Expect Before the Test

No special preparation is needed. A healthcare provider will take a small blood sample or provide a saliva collection kit to collect DNA for analysis.

What to Expect After the Test

Results may indicate whether you carry specific cystic fibrosis mutations, which can guide decisions about prenatal testing, family planning, or monitoring for symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Cystic Fibrosis Mutation Probe Test

Frequently asked questions

What does a positive result mean?
A positive result means the test detected specific cystic fibrosis-related mutations in your DNA. This may raise concerns about passing these mutations to children, so genetic counseling is recommended to discuss next steps.
What if the test is negative?
A negative result means the tested mutations were not detected in your DNA. However, cystic fibrosis can be caused by other mutations, so further genetic testing may still be advised if symptoms or family history suggest a risk.
Is this test covered by insurance?
Coverage depends on your insurance plan, medical necessity, and local healthcare policies. Check with your insurance provider or healthcare team to confirm coverage details before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy