Skip to content

C-reactive protein (CRP) by nephelometry (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

CRP helps doctors assess inflammation, often used to monitor conditions like infections or autoimmune diseases.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
106058-1
Short code
CT + NG + TV rRNA Pnl Vagina NAA+probe
Synonyms
CT + NG + TV rRNA Pnl Vagina NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is C-Reactive Protein (CRP) Used For?

CRP is primarily used to detect and monitor inflammation. High levels may signal infections, injuries, or conditions like rheumatoid arthritis, lupus, or heart disease. It can also help track how well treatments are working for certain inflammatory conditions.

How Is CRP Tested?

The test involves drawing blood from a vein in your arm. The blood is then processed to measure CRP levels using a specialized nephelometry method, which detects the protein’s presence in your serum or plasma.

What Does a CRP Test Tell You?

While CRP doesn’t specify the cause of inflammation, elevated levels often point to an active inflammatory process. Very high levels may indicate severe infections or complications from conditions like sepsis. Low or normal levels suggest minimal inflammation, but they don’t rule out other causes.

When Might You Need a CRP Test?

Your doctor may order a CRP test if you have symptoms like fever, joint pain, or unexplained fatigue, or if you’re at risk for conditions like heart disease, autoimmune disorders, or chronic infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP is a general marker of inflammation and is used to guide treatment decisions, monitor disease activity, and assess response to therapy in conditions like arthritis, cardiovascular disease, or post-surgical recovery. It’s not diagnostic on its own but often helps narrow down possible causes of symptoms.

Short name

CRP

Frequently asked questions

Why might my CRP test be higher than usual?
Higher CRP levels can result from infections (like pneumonia or urinary tract infections), injuries, surgeries, autoimmune diseases (like rheumatoid arthritis), or other inflammatory conditions. Stress, certain medications, or recent blood draws can also temporarily affect results.
What should I do if my CRP test is elevated?
If your CRP is elevated, your doctor may recommend further testing or treatments to address the underlying cause. Follow their advice closely, including lifestyle changes or medications if prescribed. Avoid smoking and limit alcohol, as these can worsen inflammation.
Can CRP test results change over time?
Yes, CRP levels can fluctuate. They may rise quickly during acute infections or injuries and gradually return to normal as the body heals. Regular monitoring can help track progress, especially in chronic conditions like arthritis or heart disease.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy