Cerebrospinal Fluid (CSF) Protein Profile (Posterior Fossa Fluid)
This test measures the protein content in cerebrospinal fluid, which is the fluid surrounding your brain and spinal cord. Proteins in CSF can help identify issues like inflammation, infections, or blood leaks in the brain.
["Protein levels in CSF may indicate underlying neurological conditions or damage to the brain’s protective barrier."]
Key facts at a glance
- LOINC
- 36055-2
- Short code
- CT Post fossa
- Synonyms
- CT Post fossa
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ct
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like severe headaches, neurological problems (such as weakness, numbness, or vision changes), or if they suspect conditions like meningitis, brain tumors, or bleeding in the brain. It helps assess the health of the fluid protecting your brain and spinal cord.
What to Expect Before the Test
You’ll likely have a small needle inserted into your back to collect a sample of CSF. This is usually done in a hospital or clinic setting. You may feel mild pressure afterward, but it’s generally quick and painless.
What the Results Mean
High protein levels in CSF might suggest inflammation, infection, or blood leakage. Low levels could indicate normal fluid composition or rare conditions. Your doctor will interpret results in relation to your symptoms and medical history.
Common Conditions Affecting Results
Conditions like multiple sclerosis, brain tumors, or traumatic brain injury can alter CSF protein levels. Infections (e.g., meningitis) or bleeding in the brain may also change these readings.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Protein Levels
Frequently asked questions
How often will I need this test?
What does a normal range mean for me?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy