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Protein Electrophoresis (Serum/Plasma) with Bromocresol Green (BCG) Dye Binding Assay

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of proteins in your blood using a dye that binds to specific protein fractions, helping identify abnormalities in protein levels.

Quick summary

["Assesses protein patterns that may indicate conditions like liver disease, kidney problems, or other metabolic disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78987-5
Short code
CT-proAVP SerPl IA-sCnc
Synonyms
CT-proAVP SerPl IA-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses bromocresol green (BCG) dye to separate and quantify different protein fractions in your blood. Proteins are separated based on size and charge, allowing for the detection of abnormal protein patterns that may not be visible with standard blood tests. This method can help identify conditions affecting protein synthesis, breakdown, or transport in your body.

How the Test Works

Blood is drawn and processed to separate serum or plasma. The BCG dye binds to specific protein groups (e.g., albumin, globulins) and shifts color proportionally to their concentration. The resulting color change is measured to determine protein levels and ratios.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions such as liver disease (e.g., cirrhosis), kidney disease, multiple myeloma, or other disorders that alter protein production or metabolism.

Sample Preparation

A blood sample is collected in a special tube to separate serum or plasma. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Protein Electrophoresis

Frequently asked questions

How long will it take to get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss findings with you during your follow-up visit.
What does an abnormal result mean?
Abnormal results may indicate imbalances in protein fractions, such as low albumin (common in liver or kidney disease) or elevated globulins (possible in inflammatory conditions or myeloma). Always discuss results with your doctor for personalized interpretation.
Can I eat or drink before this test?
Standard fasting rules may apply, but confirm with your doctor or lab technician. Avoid alcohol or certain medications that could interfere with results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy