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C-reactive protein (serum/plasma) concentration, measured by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein (CRP) in your blood. CRP is a protein produced by your liver in response to inflammation, helping your immune system fight infections and injuries.

Quick summary

["CRP helps doctors assess inflammation and identify potential infections or autoimmune conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109732-8
Short code
C trach Ag Msmt Cvx
Synonyms
C trach Ag Msmt Cvx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP is Tested

Doctors may order a CRP test to monitor conditions like infections (e.g., pneumonia, urinary tract infections), inflammatory diseases (e.g., rheumatoid arthritis, lupus), or to check for signs of tissue damage or healing after surgery or injury. It can also help evaluate responses to treatments.

How the Test Works

Your blood sample is sent to a lab where it is analyzed using nephelometry, a method that detects the amount of CRP in your serum or plasma. The test measures the protein’s concentration, which is then compared to a reference range to determine your results.

What to Expect Before the Test

You can typically have this test done at a doctor’s office, clinic, or lab. No special preparation is usually needed, but you may be asked to fast for 8–12 hours if your doctor specifies it for other tests. Avoid strenuous activity or recent infections before the test if instructed.

What the Results Mean

Results are reported in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). Higher CRP levels often indicate inflammation, while lower levels suggest minimal or no inflammation. Your doctor will interpret results based on your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (NONE)

Frequently asked questions

What does a high CRP level mean?
A high CRP level can signal an active infection, such as an infection in your lungs, kidneys, or urinary tract. It may also indicate conditions like autoimmune diseases (e.g., rheumatoid arthritis), heart disease, or other inflammatory processes. Your doctor will consider the context, such as symptoms and other test results, to determine the cause.
What does a low CRP level mean?
A low CRP level usually means there is little to no inflammation in your body. However, it doesn’t rule out all infections or conditions—your doctor may still investigate further if you have symptoms. Chronic low CRP levels might be normal for some people, but repeated testing can help track health trends.
Can CRP levels change over time?
Yes, CRP levels can fluctuate based on your health status. For example, they may rise after surgery, injury, or during flare-ups of chronic conditions like arthritis. Regular monitoring can help track how well treatments are working or if inflammation is worsening or improving.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy