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C-reactive protein, serum/plasma concentration (high-sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of a protein called C-reactive protein in your blood. It helps assess inflammation, which can occur due to infections, injuries, or other health conditions.

Quick summary

["hs-CRP helps track inflammation, aiding early detection of risks like heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108315-3
Short code
C trach Ag Msmt UrnS
Synonyms
C trach Ag Msmt UrnS
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to monitor chronic conditions like heart disease, arthritis, or other inflammatory diseases. It can also help evaluate responses to treatments or detect early signs of infection or injury.

What Does a High or Low Level Mean?

High levels may signal inflammation or infection, while low levels typically indicate no significant inflammation. However, results depend on your overall health and medical history.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure hs-CRP levels using a sensitive immunoassay method.

What Are Common Causes of Abnormal Results?

Increased levels can be caused by infections, autoimmune diseases, trauma, or certain medications. Decreased levels may occur with chronic inflammation suppression or certain genetic conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your health needs, such as monitoring heart disease risk or managing chronic conditions. Follow their advice for scheduling.
What should I do if my hs-CRP level is elevated?
If your level is elevated, discuss it with your healthcare provider. They may recommend lifestyle changes, further testing, or treatments to address underlying causes or reduce inflammation.
Does diet or exercise affect hs-CRP levels?
Yes, lifestyle factors like diet, exercise, and smoking can influence inflammation. Improving these habits may help lower hs-CRP levels over time, but results vary by individual.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy