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Serum Creatinine (Creatinine Level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of creatinine, a waste product from muscle metabolism that your kidneys filter out of your blood. It helps assess kidney function.

Quick summary

["A creatinine test checks how well your kidneys are working by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109178-4
Short code
C trach B Ab Msmt Ser
Synonyms
C trach B Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally removed by your kidneys. High levels can indicate kidney problems, while low levels might suggest dehydration or muscle loss. This test is often used alongside other measures, like blood urea nitrogen (BUN), to evaluate kidney health.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into a vein (usually in your arm) to draw blood. If you’re dehydrated, your doctor might advise drinking extra fluids the day before. Avoid strenuous exercise or heavy meals before the test.

What the Results Mean

Results are typically reported in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). While reference ranges vary by lab, higher than expected levels may signal kidney issues, while very low levels could raise concerns about hydration or muscle metabolism. Your doctor will interpret results in the context of your overall health.

Common Causes of Abnormal Results

High creatinine levels may be due to kidney disease, dehydration, or conditions that reduce blood flow to the kidneys. Low levels might result from overhydration, muscle wasting, or certain medications. Other factors, like diet (high-protein foods) or recent exercise, can also influence results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine

Frequently asked questions

How often do I need this test?
Your doctor may order this test periodically if you have kidney-related symptoms, a history of kidney disease, or conditions like diabetes or high blood pressure. Some people with chronic conditions get it checked regularly to monitor kidney function over time.
Can diet affect my creatinine levels?
Yes, eating a high-protein diet or consuming large amounts of meat can temporarily raise creatinine levels. Your doctor may suggest timing your test after a normal meal or avoiding heavy protein intake for a day before testing to get a more accurate reading.
What should I do if my creatinine level is high?
If your test results show elevated creatinine, your doctor will likely review your medical history, other test results, and lifestyle factors. They may recommend adjustments to your diet, hydration, or treatment plan for underlying conditions like kidney disease or heart problems. Follow-up tests may be needed to track progress.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy