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C-reactive protein (CRP) concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, guiding treatment for conditions like infections, autoimmune diseases, or heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13217-5
Short code
C trach B Ab Ser-aCnc
Synonyms
C trach B Ab Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is CRP Tested?

Doctors may order a CRP test to check for signs of inflammation, monitor chronic conditions, or evaluate symptoms like fever, joint pain, or unexplained fatigue. It’s often used alongside other tests to assess risk for heart disease or to guide treatment decisions in conditions like rheumatoid arthritis or infections.

What Does CRP Measure?

CRP is a marker of inflammation. When your body detects harmful substances, such as bacteria or damaged cells, it triggers CRP production. Higher CRP levels may indicate active inflammation, but they can also rise gradually in some chronic health conditions.

How Is the CRP Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure CRP concentration. The test typically takes a few hours to complete, and results are compared to general reference ranges.

What Are Common Uses of CRP?

CRP is commonly used to monitor inflammation in conditions like infections (e.g., pneumonia, urinary tract infections), autoimmune diseases (e.g., lupus, rheumatoid arthritis), and cardiovascular risks. It may also help assess response to treatment or detect early signs of disease progression.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP’s Role in Health and Disease

Short name

CRP

Frequently asked questions

How soon after symptoms will I get my CRP results?
CRP results are usually available within 24 to 48 hours after the blood draw, depending on lab processing times. Your doctor will discuss the results with you, including whether they are within normal ranges or if further testing or follow-up is needed.
What does a high CRP level mean?
A high CRP level suggests inflammation is present. While it can indicate infections, injuries, or autoimmune activity, it doesn’t always pinpoint the exact cause. Your doctor will consider your symptoms, medical history, and other test results to interpret the results accurately.
Can CRP levels change with diet or lifestyle?
Yes, lifestyle factors like diet, exercise, and smoking can influence CRP levels. Reducing inflammation through healthy eating, regular activity, and avoiding smoking may help lower CRP levels over time, though results may take weeks or months to reflect changes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy