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C-reactive protein (high-sensitivity) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein in your blood that rises when your body is fighting inflammation or infection.

Quick summary

["hsCRP helps track inflammation, often used before or after other tests for conditions like heart disease or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110054-4
Short code
C trach B IgG Msmt Ser
Synonyms
C trach B IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order this test to monitor inflammation in your body, especially if you have a history of heart disease, arthritis, or other inflammatory conditions. It can also be used to check for signs of infection or to evaluate how well treatments are working for conditions like lupus or rheumatoid arthritis.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm to draw blood. It usually takes about 15 minutes total, and you can eat and drink normally afterward. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results are reported in milligrams per liter (mg/L). Higher levels may indicate inflammation, infection, or other health concerns. Very low levels might suggest no active inflammation. Your doctor will interpret the results in the context of your overall health and medical history.

Common Conditions Monitored

High-sensitivity CRP is often used to assess risk for heart disease, track progression of autoimmune diseases, or evaluate responses to treatments for conditions like vasculitis or certain types of arthritis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

hsCRP is a marker for systemic inflammation, which can signal underlying health risks such as cardiovascular disease, certain cancers, or chronic inflammatory diseases. While not a definitive test, it provides valuable insight for doctors to guide treatment decisions and monitor disease activity over time.

Short name

hsCRP

Frequently asked questions

What does a high hsCRP level mean?
A high hsCRP level suggests increased inflammation in your body, which may be linked to conditions like heart disease, infections, or autoimmune disorders. Your doctor will discuss this with you and may recommend further testing or adjustments to your treatment plan.
Can I eat or drink anything before this test?
Yes, you can eat and drink normally before this test. No special diet or fasting is required.
How long will it take to get my results?
Results are typically available within a few days to a week, depending on your lab’s processing schedule. Your doctor will contact you with the final results once they are ready.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy