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C-reactive protein (CRP) mass concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13218-3
Short code
C trach C Ab Ser-aCnc
Synonyms
C trach C Ab Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is C-Reactive Protein (CRP) Used For?

CRP is primarily used to detect inflammation in your body. High levels may signal infections (such as pneumonia or urinary tract infections), autoimmune diseases (like rheumatoid arthritis), or other inflammatory conditions. It can also help assess how well your body is responding to treatment for these conditions or after procedures like surgery or a heart attack.

When Might You Need This Test?

Your healthcare provider may order a CRP test if you have symptoms of inflammation, such as fever, pain, or swelling, or if you’re being evaluated for conditions like heart disease, infections, or autoimmune disorders. It’s also sometimes used as a screening tool before certain procedures.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The blood is then sent to a lab, where it’s analyzed to measure the CRP levels. The test typically takes a few hours to complete, and results are usually available within a day or two.

What Do CRP Results Mean?

CRP results are reported in milligrams per liter (mg/L). While reference ranges can vary slightly by lab, higher than normal levels may indicate inflammation, while lower levels suggest reduced inflammation. Your healthcare provider will interpret the results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (Serum/Plasma)

Frequently asked questions

Why might my CRP test be ordered?
Your provider may order this test to check for inflammation, monitor chronic conditions, or evaluate how your body is responding to treatment. For example, it’s often used to assess heart disease risk or to monitor autoimmune diseases like lupus or rheumatoid arthritis.
What does a high CRP level mean?
A high CRP level often signals inflammation, which can be caused by infections, injuries, autoimmune diseases, or other conditions. However, it’s not always a direct indicator of a specific disease—your provider will consider other factors, like symptoms and medical history.
Can CRP levels change over time?
Yes, CRP levels can fluctuate depending on your health status, recent infections, medications, or other factors. If you’ve had recent surgery, illness, or changes in treatment, your results may reflect those changes rather than a stable health condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy