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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27370-6
Short code
C trach C Ab Titr Ser IF
Synonyms
C trach C Ab Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your kidneys normally filter waste products like creatinine from your blood. High levels may indicate kidney problems, while low levels could suggest muscle disorders or dehydration. This test is often used alongside other kidney function tests to diagnose or monitor conditions like chronic kidney disease.

What to Expect Before the Test

You’ll typically have a small blood sample drawn from a vein in your arm. No special preparation is usually needed, but inform your healthcare provider if you’re taking certain medications or have recent muscle injuries.

Common Conditions Monitored

This test is commonly used to monitor kidney function in conditions like chronic kidney disease, acute kidney injury, or after treatments that may affect kidney health, such as certain medications or surgeries.

Factors That Can Affect Results

Several factors can influence creatinine levels, including muscle mass (higher muscle mass may raise levels), dehydration or fluid overload, certain medications, and recent exercise or muscle damage.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Creatinine

Frequently asked questions

What does a high creatinine level mean?
A high creatinine level may suggest your kidneys are not working as well as they should, which can be an early sign of kidney disease or other health problems. Your doctor will discuss this with you and may recommend additional tests or treatments.
Do I need to fast for this test?
No fasting is required for this blood test. However, inform your healthcare provider about any medications you’re taking or recent changes in your health, such as muscle injuries or illnesses.
How often should I get this test?
Your doctor will determine how often you need this test based on your health status. Regular monitoring may be recommended if you have kidney disease, diabetes, or other conditions that affect kidney function.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy