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Conjunctival Conjunctival Antibody Probe (IgA, IgG, IgM) – Immunofluorescence

Published: August 9, 2026Updated: August 16, 2026

This test detects specific antibodies in your eye’s conjunctiva, which may help diagnose certain inflammatory or infectious eye conditions.

Quick summary

["It helps identify immune responses linked to conditions like dry eye syndrome or autoimmune-related eye diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
21187-0
Short code
C trach DNA Conjunct Ql NAA+probe
Synonyms
C trach DNA Conjunct Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a probe to detect antibodies (IgA, IgG, and IgM) in the conjunctival fluid. These antibodies can indicate an immune response to inflammation, infection, or autoimmune processes affecting the eyes.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like redness, irritation, or discharge in the eye, or if you have a suspected condition like Sjögren’s syndrome, dry eye disease, or other ocular autoimmune disorders.

Sample Collection and Preparation

A small sample of fluid from your conjunctiva (the clear tissue covering the white part of your eye) is collected using a sterile swab. This is a quick, painless procedure done in a clinical setting.

What to Expect Before the Test

No special preparation is needed. You may be asked to blink gently to help expose the conjunctiva, but avoid touching or irritating your eyes before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results for specific antibodies may suggest an underlying autoimmune or inflammatory condition affecting the eyes. This can guide treatment decisions, such as managing dry eye, reducing inflammation, or monitoring immune-related eye diseases.

Short name

Conjunctival Immunofluorescence Antibody Test

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of certain antibodies in your conjunctival fluid, which may suggest an immune response. This could point toward conditions like dry eye syndrome, autoimmune disorders, or other inflammatory eye diseases. Further evaluation by your healthcare provider is needed to determine the exact cause and next steps.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I take anything before this test?
No special preparations are required. Avoid using eye drops or applying any substances to your eyes before the test to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy