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Quantitative detection of specific DNA sequences in serum/plasma using probe-based amplification

Published: August 9, 2026Updated: August 16, 2026

This test measures certain DNA fragments in your blood to identify specific genetic markers, often used to detect infections, genetic mutations, or other molecular abnormalities.

Quick summary

["Helps diagnose conditions by detecting unique genetic sequences in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43404-3
Short code
C trach DNA Spec Ql Probe+sig amp
Synonyms
C trach DNA Spec Ql Probe+sig amp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-sig
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test uses specialized probes to detect and quantify specific DNA sequences in your serum or plasma. The probes bind to target DNA fragments, allowing for precise identification and measurement. This method is particularly useful for detecting pathogens, genetic variants, or other molecular markers that may not be visible through traditional blood tests.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms suggestive of an infection, genetic disorder, or other conditions where specific DNA sequences play a role. It can also be used for monitoring certain treatments or conditions that involve genetic markers.

Common Uses

Common applications include identifying viral infections (e.g., certain bacteria, viruses), detecting genetic mutations linked to hereditary diseases, or monitoring chronic conditions where DNA markers are relevant.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is sent to the lab for testing. This process helps ensure accurate detection of the DNA sequences.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

DNA Probe Test (Serum/Plasma)

Frequently asked questions

This test provides detailed molecular information that can help confirm diagnoses, guide treatment decisions, or assess disease progression. It may be particularly useful in cases where traditional tests are inconclusive or where genetic factors are suspected.
How accurate is this test? This test is highly sensitive and specific for detecting the targeted DNA sequences, but results should always be interpreted by a healthcare professional in the context of your overall health and medical history.
What does a positive result mean? A positive result indicates the presence of the specific DNA sequences being tested for, which may suggest an infection, genetic mutation, or other underlying condition. Your doctor will discuss the implications with you based on your symptoms and test results.
How long does it take to get results? Results from this test are typically available within a few days to a week, depending on lab processing times and any follow-up steps required.
Is there any preparation needed before the test? Generally, no special preparation is required for this test. However, you may be asked to avoid certain medications or foods if your doctor specifies, as they could affect test results.
Are there any risks or side effects? Blood draws are generally safe, but you may experience mild discomfort or bruising at the injection site. Rarely, there could be a slight reaction or infection at the site, but these are uncommon.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy