C-reactive protein (CRP) with high-sensitivity measurement (serum/plasma)
This test measures a protein in your blood that rises when your body is fighting inflammation, often used to monitor or detect low-grade inflammation or infection.
["hs-CRP helps track inflammation, aiding early detection of conditions like heart disease or autoimmune disorders."]
Key facts at a glance
- LOINC
- 90358-3
- Short code
- C trach+GC pnl Anorectl NAA+probe
- Synonyms
- C trach+GC pnl Anorectl NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why hs-CRP Matters in Health Monitoring
High-sensitivity CRP (hs-CRP) is a blood test that detects small amounts of a protein called C-reactive protein. CRP is produced by your liver in response to inflammation, which can occur due to infections, injuries, or chronic conditions like arthritis or heart disease. This test is particularly useful because it can identify subtle, long-term inflammation that might not be obvious otherwise.
How the Test Works
Your blood sample is drawn and analyzed using a sensitive immunoassay method to measure CRP levels. The test is designed to pick up very low concentrations of CRP, which is why it’s called high-sensitivity.
Common Uses for hs-CRP
Doctors often use hs-CRP to assess risk for cardiovascular diseases, monitor chronic inflammatory conditions, or evaluate the effectiveness of treatments for conditions like rheumatoid arthritis or other autoimmune diseases.
What Normal Results Mean
While reference ranges can vary by lab, lower CRP levels generally indicate minimal inflammation. Elevated levels may signal inflammation or infection, prompting further investigation. Your doctor will interpret results in the context of your overall health and symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Inflammation and Disease Risk
Short name
hs-CRP
Frequently asked questions
What does a high hs-CRP level mean?
Can hs-CRP be used to diagnose a specific condition?
How often should I get an hs-CRP test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy