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C-reactive protein (CRP) concentration, plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein in your blood plasma. CRP is a protein produced by your liver in response to inflammation, helping your body identify and fight infections or injuries.

Quick summary

["CRP helps track inflammation, guiding decisions about treatment or further testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70163-1
Short code
C trach+GC pnl Cvx NAA+probe
Synonyms
C trach+GC pnl Cvx NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for signs of inflammation, monitor conditions like rheumatoid arthritis, infections, or heart disease, or evaluate responses to treatments. It can also help assess risk for certain health issues over time.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a broader panel, but this isn’t always required for CRP alone. Bring any medications you’re currently taking.

How the Test Works

A small blood sample is drawn from a vein, typically in your arm. The blood is processed to separate plasma, which is then tested for CRP levels using a sensitive immunoassay method to detect even small amounts of the protein.

What the Results Mean

Results are reported in milligrams per liter (mg/L). Higher than normal levels may indicate inflammation, infection, or other underlying conditions. Your provider will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP is a marker of systemic inflammation. Elevated levels may signal acute infections (e.g., pneumonia), chronic inflammatory diseases (e.g., lupus), or conditions like cardiovascular disease. It’s often used alongside other tests to guide treatment plans, such as adjusting medications or identifying risk factors for long-term health concerns.

Short name

CRP (Plasma)

Frequently asked questions

What causes CRP levels to rise?
CRP levels can increase due to infections (like colds or urinary tract infections), injuries, surgeries, or certain medications. Chronic conditions such as arthritis, heart disease, or autoimmune disorders may also lead to higher CRP over time.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will contact you once they’re ready to discuss the findings.
Can I lower my CRP levels naturally?
Yes! Reducing inflammation may involve lifestyle changes like improving diet (e.g., Mediterranean diet), increasing physical activity, managing stress, and avoiding smoking. If inflammation is linked to an underlying condition, your provider may recommend specific treatments.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy