Skip to content

C-reactive protein (CRP) by turbidimetry (high-sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called C-reactive protein, which your body produces in response to inflammation. It helps doctors assess whether inflammation is present in your bloodstream.

Quick summary

["hs-CRP helps track inflammation, a key marker for conditions like infections, autoimmune diseases, or heart risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45067-6
Short code
C trach+GC rRNA Cvx Ql Probe
Synonyms
C trach+GC rRNA Cvx Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test measures high-sensitivity C-reactive protein (hs-CRP), a substance your liver produces when there is inflammation in your body. Your doctor may order it to help assess your risk of heart disease or stroke, to check for inflammation, or to see how well a treatment is working over time.

Your doctor may order this test to check for signs of inflammation, monitor conditions like rheumatoid arthritis, heart disease, or infections, or evaluate responses to treatments. High levels may signal underlying issues needing attention.

Higher hs-CRP levels generally mean there is more inflammation somewhere in your body. A result above 3.0 mg/L has been associated with an increased risk of cardiovascular problems, while a low value suggests lower risk. Your doctor will interpret your number together with your other test results, symptoms, and overall health history.

Results are not given in absolute numbers here, but doctors compare them to your specific health context. Elevated levels often indicate active inflammation, while lower levels suggest reduced inflammation. Always discuss results with your healthcare provider.

The sample is collected with a simple blood draw. A healthcare professional will clean the skin on the inside of your elbow, wrap a band around your upper arm, and insert a small needle into a vein to collect blood into a tube. The procedure usually takes only a few minutes and causes little discomfort.

A blood sample is drawn from a vein, usually in your arm. You may feel a brief pinch, but it’s quick. The sample is sent to a lab for analysis.

In most cases, no special preparation is needed and fasting is not required. However, tell your doctor about any recent illness, infection, injury, vigorous exercise, or vaccination, since these can temporarily raise hs-CRP levels. Also mention all prescription medicines, vitamins, and supplements you currently take.

Avoid strenuous activity or intense exercise 24 hours before testing, as it may temporarily raise inflammation markers. Also, inform your doctor about any medications or supplements you’re taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

hs-CRP is a marker for systemic inflammation. Chronic, low-grade inflammation is linked to conditions like cardiovascular disease, diabetes, and certain cancers. Doctors use it to guide treatment plans and monitor long-term health risks.
What are typical reference ranges? For hs-CRP, results below 1.0 mg/L are generally considered low risk, 1.0 to 3.0 mg/L indicates average risk, and values above 3.0 mg/L suggest high cardiovascular risk. A result above 10.0 mg/L may point to an acute infection or active inflammation and is often repeated later.
Reference ranges vary by lab and individual health status. A low hs-CRP level (typically below 1 mg/L) suggests minimal inflammation, while higher levels (above 3 mg/L) may indicate more significant inflammation. Your doctor will interpret results in the context of your health.
Can lifestyle changes affect hs-CRP levels? Yes, they can. Regular physical activity, gradual weight loss, quitting smoking, following a heart-healthy diet, and managing conditions such as diabetes or high blood pressure can help lower hs-CRP levels over time and may reduce your overall cardiovascular risk.
How often should I get this test?
Frequency depends on your health needs. Your doctor will determine how often to check hs-CRP based on your condition, symptoms, or treatment plan. Regular monitoring may be recommended for chronic conditions like heart disease or autoimmune disorders.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy