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C-reactive protein (CRP) quantitative measurement by probe-based immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called C-reactive protein (CRP), which your body produces in response to inflammation. CRP helps doctors assess whether you have low-grade inflammation that may be affecting your health.

Quick summary

["CRP helps track subtle inflammation linked to heart disease, infections, or autoimmune conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45074-2
Short code
C trach+GC rRNA Ur Ql Probe
Synonyms
C trach+GC rRNA Ur Ql Probe
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for signs of inflammation, especially if you have risk factors for heart disease, such as high blood pressure or diabetes. It can also help monitor conditions like rheumatoid arthritis, lupus, or other inflammatory diseases. Sometimes, it’s used to evaluate symptoms like fever, joint pain, or unexplained fatigue without a clear cause.

What Does a High or Low CRP Level Mean?

A higher CRP level often means your body is fighting inflammation. For example, it may rise after an infection, injury, or during flare-ups of certain diseases. A very low CRP level might suggest your inflammation is under control, but it doesn’t always mean you’re healthy. Always discuss results with your doctor.

Sample Collection and Preparation

This test uses a blood sample drawn from a vein in your arm. The blood is processed to separate the serum (liquid part) for testing. No special preparation is needed, but tell your doctor about any medications or recent illnesses that might affect results.

What to Expect During the Test

You’ll likely sit or lie down while a healthcare provider inserts a small needle into your arm to draw blood. The process usually takes a few minutes. You may feel a slight pinch, but most people tolerate it well. Afterward, you can resume normal activities.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP is a marker for systemic inflammation, meaning it reflects widespread reactions in your body. High levels can signal conditions like cardiovascular disease, infections, or autoimmune disorders. Doctors use it as a screening tool or to guide treatment decisions, especially for chronic conditions. However, CRP alone isn’t diagnostic—it’s often used alongside other tests and clinical findings.

Short name

CRP (High-Sensitivity)

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health status, symptoms, and medical history. For example, people with heart disease or autoimmune conditions might get it more frequently than others. Follow their advice, as testing schedules can vary widely.
Can lifestyle changes affect CRP levels?
Yes, lifestyle factors like diet, exercise, and smoking can influence CRP levels. Eating a heart-healthy diet, staying active, and avoiding smoking may help lower inflammation. Stress management and adequate sleep also play a role, though results depend on individual health.
What if my CRP level is in the normal range but I still feel unwell?
A normal CRP level doesn’t always mean you’re healthy. Inflammation can be subtle, and other markers or symptoms may be needed to diagnose the cause of your discomfort. Always share your symptoms and concerns with your doctor—they may recommend additional tests or a different approach.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy