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C-reactive protein (CRP) measured by high-performance liquid chromatography (HPLC) or a related quantitative method in urine

Published: August 9, 2026Updated: August 16, 2026

This test checks for elevated levels of C-reactive protein in your urine, which may indicate inflammation or infection in your body.

Quick summary

["Urine CRP helps detect systemic inflammation that could signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45075-9
Short code
C trach+GC rRNA Urth Ql Probe
Synonyms
C trach+GC rRNA Urth Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, pain, or signs of infection, or if they suspect conditions like kidney disease, autoimmune disorders, or other inflammatory conditions. It can also be part of routine monitoring for certain chronic illnesses.

What to Expect Before the Test

No special preparation is needed. You’ll provide a urine sample, typically collected in the morning. Avoid excessive exercise or strenuous activity 24 hours before testing.

What the Results Mean

Higher-than-normal CRP in urine may signal inflammation, infection, or kidney issues. However, elevated levels alone don’t confirm a specific diagnosis without clinical correlation. Your provider will interpret results in the context of your symptoms and medical history.

Common Conditions Linked to Urine CRP

Elevated urine CRP can be associated with systemic inflammation, kidney disease, urinary tract infections, or conditions like lupus or rheumatoid arthritis. It’s not specific to any one condition, so results are used alongside other tests and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Urine CRP is a less common but useful marker for detecting inflammation in the urinary tract or systemic conditions. It may complement traditional CRP testing in certain diagnostic scenarios, particularly when kidney function or urinary tract involvement is suspected.

Short name

Urine CRP Probe

Frequently asked questions

Why might my urine CRP test be ordered even if I don’t have obvious symptoms?
Your provider may order it to monitor chronic conditions (like kidney disease or autoimmune disorders), screen for early inflammation, or investigate unexplained symptoms like frequent urination, pain, or fatigue.
Can urine CRP levels change based on diet or hydration?
Yes, hydration status and certain foods (like high-sodium diets) may influence urine volume and concentration, but they typically don’t affect CRP levels directly. Follow your provider’s advice on timing your sample for accuracy.
Is urine CRP the same as blood CRP?
No. Urine CRP measures protein in your urine, while blood CRP measures protein in your bloodstream. Both can indicate inflammation, but they serve different diagnostic purposes depending on the suspected condition.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy