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Serum Creatinine (Creatinine Level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function check via creatinine levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109169-3
Short code
C trach G+F+K Ab Msmt Ser
Synonyms
C trach G+F+K Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out of your blood by your kidneys. High levels can indicate reduced kidney function, while low levels may suggest overhydration or other conditions. This test is often used alongside other measures, like blood urea nitrogen (BUN), to evaluate kidney health.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually causes only minor discomfort. If you’re dehydrated or have recently eaten a large meal, your results might be affected, so it’s best to drink water and eat normally the day of testing.

What the Results Mean

Results are interpreted in relation to your overall health, age, sex, and other medical conditions. While creatinine levels alone don’t diagnose kidney disease, they’re part of a broader assessment. Your healthcare provider will discuss any changes in your results with you.

Common Causes of Abnormal Results

High creatinine levels may signal kidney problems, dehydration, or muscle disorders. Low levels might suggest overhydration, liver disease, or certain medications. Other factors, like diet (high-protein foods) or exercise, can temporarily influence results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine is a critical marker for kidney function. Chronic kidney disease (CKD) is often detected early through repeated monitoring of creatinine and BUN levels. Abnormal results prompt further evaluation, such as additional blood tests, imaging, or urine tests, to identify underlying causes and guide treatment.

Short name

Creatinine

Frequently asked questions

How often should creatinine levels be checked?
Your doctor will determine how often to check creatinine levels based on your health status. People with kidney disease, diabetes, or high blood pressure may need more frequent tests, while others with stable health may only need occasional checks.
What can affect my creatinine test results?
Several factors can influence creatinine levels, including dehydration or overhydration, recent intense exercise, high-protein meals, or certain medications. If you suspect these factors may have impacted your results, discuss them with your healthcare provider.
Can creatinine levels change over time?
Yes, creatinine levels can fluctuate due to changes in kidney function, hydration status, or muscle mass. Regular monitoring helps track trends, especially in people at risk for kidney disease or those undergoing treatments that affect kidney health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy