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C-reactive protein (CRP) with high-sensitivity measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of a protein called C-reactive protein in your blood, which helps assess inflammation in your body.

Quick summary

["hs-CRP helps doctors check for signs of inflammation, often used to monitor conditions like heart disease risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110056-9
Short code
C trach G+F+K IgM Msmt Ser
Synonyms
C trach G+F+K IgM Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why hs-CRP Matters in Your Health

Inflammation is your body’s way of responding to injury or infection, but sometimes it can become chronic and affect conditions like heart disease, arthritis, or autoimmune disorders. hs-CRP is a sensitive marker for low-level inflammation that may not be detected by other tests.

How the Test Works

A small blood sample is taken from your arm, and the lab uses a highly sensitive method to measure CRP levels. This test is often ordered to monitor ongoing health risks or to guide treatment decisions.

What to Expect Before the Test

No special preparation is needed, but you may want to avoid strenuous activity or heavy meals 24 hours before the test. If you’re on blood thinners or have recent trauma, let your provider know.

Common Uses for hs-CRP

Doctors may order hs-CRP to evaluate risk for cardiovascular disease, track inflammation in conditions like rheumatoid arthritis, or monitor response to treatments for chronic illnesses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

hs-CRP is primarily used to assess the risk of heart disease or other inflammatory conditions. Higher levels may indicate increased risk, prompting further evaluation or lifestyle changes.
What does a high hs-CRP level mean?
A high hs-CRP level suggests your body is experiencing inflammation, which could be linked to conditions like heart disease, infections, or autoimmune disorders. Your doctor will interpret results in the context of your overall health.
How often should I get this test?
Your doctor will determine how often to check hs-CRP based on your medical history, symptoms, and treatment plan. Some people may need it yearly or more frequently if they have ongoing health concerns.
If your hs-CRP is elevated, your doctor may recommend lifestyle changes (like diet, exercise, or stress management), medications, or additional tests to address the underlying cause of inflammation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy