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C-reactive protein (high-sensitivity) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by the liver in response to inflammation, helping assess low-grade inflammation in your body.

Quick summary

["hs-CRP helps track inflammation, which may relate to conditions like heart disease or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44079-2
Short code
C trach IgA+IgG+IgM Ser-Imp
Synonyms
C trach IgA+IgG+IgM Ser-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to monitor chronic conditions like heart disease, rheumatoid arthritis, or other inflammatory diseases. It can also help evaluate risk for future health issues or guide treatment decisions.

What Does the Result Mean?

Results are not provided as a single numeric range since reference intervals vary by lab and patient factors. Higher levels often indicate inflammation, while lower levels suggest reduced inflammation. Your provider will interpret results in the context of your overall health.

Common Uses and Conditions

Commonly used for screening or monitoring chronic inflammation, cardiovascular risk assessment, and evaluating responses to treatments for inflammatory conditions.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The blood is processed into serum or plasma within 2 hours of collection for accurate results. Avoid strenuous activity or eating heavy meals before testing to ensure reliable results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

hs-CRP

Frequently asked questions

Higher hs-CRP levels may signal increased risk for cardiovascular events, such as heart attacks or strokes, and can help guide preventive care or medication adjustments. It’s not a definitive diagnosis but a useful marker for ongoing monitoring.
hs-CRP results are not a standalone test for diagnosing conditions like infections or infections. They are best used alongside other clinical findings and tests for a complete assessment.
What should I do if my hs-CRP is elevated?
If your results are elevated, discuss them with your healthcare provider. They may recommend lifestyle changes (like diet or exercise), further testing, or adjustments to medications to manage inflammation.
Can diet or exercise affect hs-CRP levels?
Yes, certain diets (e.g., Mediterranean-style) and regular physical activity can lower hs-CRP levels by reducing inflammation. However, results depend on overall health and other factors, so follow your provider’s guidance.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy