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C-reactive protein (CRP) by nephelometry (plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43848-1
Short code
C trach IgG Ser Ql
Synonyms
C trach IgG Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order CRP testing to check for signs of inflammation. This could be due to infections (like pneumonia or urinary tract infections), autoimmune conditions (such as rheumatoid arthritis), or other health concerns where inflammation plays a role. It may also be used to monitor treatment progress or detect early signs of problems.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast before the test if it involves drawing blood, but CRP plasma tests often don’t require fasting. Avoid strenuous activity or certain medications (like nonsteroidal anti-inflammatory drugs) for a few days before testing, as they can affect results.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. The blood will be sent to a lab where it is analyzed using nephelometry, a method that measures how much CRP is present in your plasma.

What Are the Possible Results?

Results are typically reported in milligrams per liter (mg/L). Higher CRP levels may indicate inflammation, while lower levels suggest minimal or no inflammation. Your results will be interpreted by your doctor based on your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP (Plasma)

Frequently asked questions

How Does CRP Help Doctors?
CRP is a marker for inflammation. Elevated levels can signal infections, injuries, or autoimmune diseases. It’s often used alongside other tests to guide treatment decisions, such as adjusting medications or planning further diagnostic steps.
What If My CRP Level Is High?
A high CRP level may mean you have inflammation. Your doctor will discuss possible causes with you and may recommend further tests or treatments. Common causes include infections, arthritis, or other inflammatory conditions. Follow-up care will depend on your specific situation.
What If My CRP Level Is Low?
A low CRP level usually means there is little to no inflammation detected in your blood. This can be normal, but your doctor may still want to check for other potential causes of low CRP, such as certain medications or underlying conditions. Always discuss your results with your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy