Cystatin C Quantitative Measurement (Serum/Plasma)
This test measures the level of cystatin C, a protein produced by all cells in the body. It helps assess kidney function.
["Cystatin C helps evaluate kidney health and may be used alongside other tests."]
Key facts at a glance
- LOINC
- 57287-5
- Short code
- C trach rRNA Anal Ql NAA+probe
- Synonyms
- C trach rRNA Anal Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- CPT
- 86038
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
This test is done to help your doctor check how well certain parts of your body are working, look for early signs of illness, or monitor a condition you already have. The results give your care team important information for diagnosing problems, guiding treatment decisions, and tracking your overall health over time.
Your doctor may order this test to check how well your kidneys are working. It can also be used to monitor kidney disease progression or guide treatment decisions, especially in people with conditions like chronic kidney disease or certain genetic disorders.
The sample is usually collected by drawing a small amount of blood from a vein in your arm, but depending on the test, it may instead involve a urine sample, a throat or nasal swab, or another simple method. A trained technician will perform the collection, and the process typically takes only a few minutes.
A small amount of blood is drawn from a vein, usually in your arm, by a healthcare professional. The blood sample is sent to a lab for testing.
Your result shows whether your values fall within the normal reference range. A normal result usually means there is no sign of the problem being checked for, while an abnormal result may point to a condition that needs closer attention. Your provider will explain what your specific numbers mean and whether any follow-up testing or treatment is needed.
Higher than expected levels of cystatin C may suggest kidney problems or other conditions affecting kidney function. Lower levels might indicate normal kidney function or certain metabolic conditions. Your doctor will interpret the result in the context of your overall health and medical history.
Common causes of abnormal results include infections, inflammation, dehydration, recent illness, stress, and certain medicines or supplements. Problems with organs such as the kidneys, liver, heart, or thyroid can also affect your values. Your provider will look at your result together with your symptoms and medical history to determine the most likely cause.
Elevated cystatin C levels can be linked to kidney disease, dehydration, muscle disorders, or certain medications. Lower levels might be seen in people with low muscle mass or specific genetic conditions. Always discuss any changes in your results with your healthcare provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Cystatin C
Frequently asked questions
Your doctor may use cystatin C levels to monitor kidney function, especially in patients with diabetes, hypertension, or a family history of kidney disease. It can also be useful in diagnosing conditions like polycystic kidney disease or assessing the effectiveness of treatments for kidney-related illnesses.
The frequency of this test depends on your health condition and medical needs. If you have kidney disease, your doctor may recommend testing more often to track changes over time. Ask your healthcare provider for specific instructions tailored to your situation.
Typically, you can eat and drink normally before this blood test unless your doctor instructs otherwise. Cystatin C levels are not affected by diet or fasting, so no special preparation is needed.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy