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C-reactive protein (CRP) measured by high-performance liquid chromatography (HPLC) or similar quantitative probe method

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by your body in response to inflammation, often used to check for signs of infection, injury, or autoimmune conditions.

Quick summary

["Helps detect low-level inflammation that may not show up with other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
21192-0
Short code
C trach rRNA Urth Ql Probe
Synonyms
C trach rRNA Urth Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why It’s Done

Your doctor may order this test to monitor conditions like arthritis, heart disease, or infections, or to check for inflammation after surgery, injury, or illness. High-sensitivity CRP is particularly useful for detecting early signs of inflammation in conditions like cardiovascular disease.

What to Expect

A small blood sample is taken from a vein in your arm. The test involves sending your blood to a lab for analysis. Results are typically ready within a few days.

How It Works

Your blood is analyzed to measure the concentration of C-reactive protein, a marker that rises when your body is inflamed. The test uses advanced methods to detect even small amounts of CRP.

What the Results Mean

Results help doctors assess the level of inflammation in your body. Elevated levels may indicate infection, inflammation, or other health issues. Your doctor will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High-sensitivity CRP is a key tool in identifying and managing chronic inflammation, which can contribute to diseases like heart disease, rheumatoid arthritis, and other autoimmune conditions. It’s often used alongside other tests to guide treatment decisions.

Short name

CRP (High-Sensitivity)

Frequently asked questions

What causes CRP levels to change?
CRP levels can rise due to infections (like colds or flu), injuries, surgeries, or certain medical conditions such as arthritis or heart disease. Stress, smoking, and certain medications can also affect CRP levels.
How long does it take to get results?
Results are usually available within 2 to 5 business days, depending on your lab’s processing time. Your doctor will contact you once they have the results.
Can I do anything to lower my CRP levels?
Yes! Reducing inflammation often involves lifestyle changes like eating a balanced diet, exercising regularly, quitting smoking, and managing stress. If you have a chronic condition, follow your doctor’s advice for managing symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy