Protein Electrophoresis on Serum/Plasma (Qualitative Probe)
This test measures the different types of proteins in your blood using a technique called electrophoresis. It helps identify abnormalities in protein distribution, which can signal conditions like multiple myeloma, liver disease, or kidney problems.
["This test helps doctors check for unusual protein patterns that may indicate health concerns."]
Key facts at a glance
- LOINC
- 70023-7
- Short code
- C tropicls DNA Bld Ql NAA+probe
- Synonyms
- C tropicls DNA Bld Ql NAA+probe
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Electrophoresis separates proteins in your blood based on their size and electrical charge. The test detects distinct protein bands (fractions) such as albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal patterns may suggest conditions like infections, cancers, or metabolic disorders.
Why Might You Need This Test?
Your doctor may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or changes in kidney/liver function. It’s also used to monitor conditions like multiple myeloma, amyloidosis, or chronic inflammatory diseases.
How Is the Test Performed?
A small blood sample is drawn from a vein. The serum or plasma is then placed in a gel and subjected to an electric current, causing proteins to move toward opposite charges. The resulting bands are analyzed for quantity and quality.
What Are Common Findings?
Normal results show distinct bands with expected proportions of albumin (most abundant) and other globulins. Abnormal findings may include: - **Monoclonal spikes** (e.g., M-protein) in multiple myeloma. - **Reduced albumin** (e.g., liver/kidney disease). - **Increased globulins** (e.g., infections, autoimmune disorders).
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test is critical for diagnosing and managing conditions affecting protein synthesis or breakdown. For example, a monoclonal spike can confirm multiple myeloma, while altered albumin levels may signal liver dysfunction or malnutrition. Early detection improves treatment planning.
Short name
Protein Electrophoresis
Frequently asked questions
What does a ‘protein electrophoresis’ test show?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy