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Carcinoembryonic Antigen (CEA) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of carcinoembryonic antigen, a protein that may be produced by certain types of cancer and some noncancerous conditions.

Quick summary

["CEA helps monitor cancer progression or treatment response in some cases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
69116-2
Short code
CT Sacrum+Coccyx
Synonyms
CT Sacrum+Coccyx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Carcinoembryonic Antigen (CEA)?

Carcinoembryonic antigen (CEA) is a protein found in small amounts in the blood of healthy people. It is produced by cells in the digestive tract and can also be released into the bloodstream when cancer cells grow and spread. CEA is often used as a tumor marker for certain cancers, such as colorectal, pancreatic, and lung cancers, though it can also appear in other conditions like chronic inflammation or smoking.

Why Might You Need This Test?

Your doctor may order a CEA test to check for cancer if you have symptoms like unexplained weight loss, fatigue, or changes in bowel habits. It may also be used during cancer treatment to monitor how the disease is responding or after treatment to see if it has returned. In some cases, CEA testing is done as part of a screening program for people at higher risk of certain cancers.

How Is the Test Done?

A blood sample is taken from a vein in your arm by a healthcare professional. The blood is then sent to a lab for analysis. The test measures the amount of CEA protein in your blood, which can help determine if cancer is present or if it has spread.

What Do the Results Mean?

CEA levels can vary widely depending on health conditions, treatments, and other factors. Higher than normal levels may suggest the presence of cancer or other health issues, but they are not definitive on their own. Your doctor will consider your medical history, symptoms, and other test results when interpreting the results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CEA Blood Test

Frequently asked questions

What are the normal results for this test?
There are no standard reference ranges for CEA because levels can vary greatly based on individual health, cancer stage, and treatment. Your doctor will compare your results to your baseline and other clinical findings to determine their meaning.
Can CEA levels change over time?
Yes, CEA levels can fluctuate. They may rise before cancer spreads (metastasis) or worsen, and they may drop if cancer treatment is effective. Regular monitoring is important if you have a history of cancer or are undergoing treatment.
Does diet or lifestyle affect CEA levels?
Diet and lifestyle factors, such as smoking, can influence CEA levels. Smoking is a known risk factor for elevated CEA in some cancers, so quitting may help lower levels. However, diet alone does not typically change CEA levels significantly unless it affects underlying health conditions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy