Skip to content

C-reactive protein in serum/plasma (high-sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by your liver in response to inflammation, helping assess general inflammation levels in your blood.

Quick summary

["hs-CRP helps track inflammation, which may relate to conditions like heart disease or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24913-6
Short code
CT Sinuses Ltd
Synonyms
CT Sinuses Ltd
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is High-Sensitivity C-Reactive Protein (hs-CRP)?

High-sensitivity C-reactive protein (hs-CRP) is a marker of inflammation in your body. It rises when tissues are damaged or infected, often linked to chronic conditions like arthritis or cardiovascular risks. Unlike traditional CRP, hs-CRP is more sensitive, detecting even low levels of inflammation.

Why Is This Test Done?

Doctors may order hs-CRP to evaluate risk for heart disease, monitor chronic inflammation, or check for infections. It can also help guide treatment decisions for conditions like rheumatoid arthritis or after surgery.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab where hs-CRP levels are measured using a sensitive immunoassay method to detect even small amounts of inflammation.

What Do Results Mean?

Results don’t provide a diagnosis alone but may indicate whether inflammation is present. Higher levels could signal conditions like infections, autoimmune diseases, or heart risks. Always discuss results with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

Why might my doctor ask for this test?
Your doctor may use hs-CRP to assess your risk for heart disease, monitor inflammation in chronic conditions, or evaluate response to treatment. It’s often used alongside other tests for a fuller picture of your health.
What are typical reference ranges?
There’s no single range for everyone. Results vary based on age, health, and other factors. Your doctor will interpret results in the context of your overall health and medical history.
How often should I get this test?
Frequency depends on your condition. Some people get it yearly for heart risk assessment, while others may need it more often if they have chronic inflammation or a history of heart disease.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy