Skip to content

Total Cholesterol (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood, which includes both the cholesterol your body makes and the cholesterol from foods you eat. Cholesterol is important for cell function but can build up in your arteries if levels are too high.

Quick summary

["Your cholesterol level helps assess your risk for heart disease and stroke."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36026-3
Short code
CT Upper arm-Bl
Synonyms
CT Upper arm-Bl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Cholesterol is a type of fat that your body needs to work properly, but high levels can clog your arteries over time, increasing your risk of heart problems. This test helps doctors monitor your heart health and guide treatment if needed.

What to Expect Before the Test

You may have this test drawn from a blood sample taken from your arm. No special preparation is usually needed, but you might be asked to fast (not eat or drink) for 12 hours before the test if it’s part of a lipid panel.

How the Results Are Used

Your doctor will compare your cholesterol level to healthy ranges and discuss it with you. They may recommend lifestyle changes, diet adjustments, or medications if your results suggest an increased risk for heart disease.

Common Causes of High or Low Cholesterol

High cholesterol can be influenced by diet, genetics, weight, or lack of exercise. Low cholesterol may occur due to certain medical conditions, medications, or diet. Your doctor will consider all factors when interpreting your results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High cholesterol can increase the risk of heart disease, stroke, or peripheral artery disease by promoting plaque buildup in arteries. Low cholesterol may raise concerns about nutrient deficiencies or underlying health conditions, depending on the context.

Short name

Cholesterol Level

Frequently asked questions

What does a high cholesterol level mean?
A high cholesterol level means your blood has more cholesterol than is typical. This can raise your risk of heart problems, so your doctor may recommend lifestyle changes or medications to help lower it.
How can I lower my cholesterol naturally?
Eating a heart-healthy diet (rich in fruits, vegetables, whole grains, and lean proteins), staying active, maintaining a healthy weight, and avoiding smoking can help improve cholesterol levels over time.
Do I need to fast before this test?
Sometimes yes—your doctor may ask you to fast for 12 hours before the test if it’s part of a lipid panel. Always follow their instructions to get the most accurate results.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy