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CT Brain Perfusion Without Contrast and CT Head Angiography With Contrast

Published: August 9, 2026Updated: August 16, 2026

This paired head CT evaluates brain blood flow and the head's blood vessels, helping assess conditions such as stroke, vessel narrowing, or aneurysm.

Quick summary

["The test combines brain blood-flow imaging with detailed images of the head's blood vessels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88326-4
Short code
CT WO con+Brain perf+CTA Head ves W cont
Synonyms
CT WO con+Brain perf+CTA Head ves W cont
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct-perfusion-ct-angio
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a radiology test that uses CT scanning to evaluate the brain. The brain-perfusion portion estimates blood flow in different brain regions, while the head CT angiogram shows the arteries and other blood vessels in the head and neck.

Why might I need this test?

These images may be ordered to evaluate symptoms of stroke or transient ischemic attack, such as sudden weakness, speech difficulty, or vision changes. They can also help assess suspected blood-vessel narrowing, blockage, aneurysm, or bleeding, particularly when symptoms are sudden or urgent.

How is the test performed?

You lie on a CT scanner table while X-ray images are taken. The initial head CT and brain-perfusion images may be obtained without injected contrast, while the angiogram uses iodinated contrast given through an intravenous line. The scan is usually quick, although the total visit may take longer.

How do I prepare for the test?

There is usually no fasting or bowel preparation. Tell the imaging staff if you have had an allergic reaction to iodinated contrast, have kidney disease, or are pregnant or may be pregnant, and follow any instructions provided by your care team.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Reduced or uneven blood flow on perfusion imaging may indicate that part of the brain is not receiving adequate circulation, as can occur with an acute stroke. Angiography may show a narrowed or blocked artery, an aneurysm, or another vascular abnormality. Findings should be interpreted by a radiologist in the context of symptoms and the other examination results.

Short name

Brain Perfusion CT and Head CT Angiography

Frequently asked questions

Why are two types of CT imaging performed together?
Perfusion imaging shows how blood is reaching different brain areas, while angiography shows the appearance and course of the blood vessels. Together, they provide complementary information about possible stroke or vascular disease.
Does this test involve contrast?
The brain-perfusion CT is listed as being performed without contrast, while the head CT angiogram uses iodinated contrast. The imaging center will explain the exact contrast plan and check for any prior contrast reactions or kidney problems.
Is this the same as a routine head CT?
No. It includes specialized brain-perfusion imaging and angiographic images of the head's blood vessels in addition to head CT imaging, so it provides more focused information about circulation and blood vessels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy