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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess kidney function.

Quick summary

["Your kidneys filter waste like creatinine from your blood; elevated levels may signal kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7269-4
Short code
Cucumber BasoBnd Ab Qn
Synonyms
Cucumber BasoBnd Ab Qn
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
lhr
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Creatinine?

Creatinine is a small molecule produced when your muscles break down proteins. It’s naturally excreted by your kidneys, and small amounts appear in your blood. This test checks how well your kidneys are working to remove it.

Why Is This Test Done?

Doctors order creatinine tests to monitor kidney function, especially if you have symptoms like swelling, fatigue, or changes in urine output. It’s also used before surgeries, during pregnancy, or if you have conditions like diabetes or high blood pressure.

What Does the Result Mean?

Results are compared to a general reference range (not provided here), but higher levels may indicate reduced kidney function. Very low levels could suggest muscle loss or certain medical conditions.

What Can Affect Results?

Factors like dehydration, muscle mass, or certain medications (e.g., NSAIDs) can influence creatinine levels. Recent exercise or eating a high-protein meal may temporarily raise it.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

How is this test done?
A blood sample is taken from a vein in your arm. You may feel a small pinch, but it usually doesn’t cause discomfort. The sample is sent to a lab for analysis.
Do I need to prepare for this test?
No special preparation is needed, but avoid excessive protein intake or strenuous exercise 24 hours before the test, as these can temporarily affect results.
Can I drink water before this test?
Yes, but avoid overhydration, as it may dilute creatinine levels. Drink as usual unless instructed otherwise by your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy