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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to certain allergens.

Quick summary

["IgE levels help identify potential allergies or immune system sensitivities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61329-9
Short code
Cucumber IgE/IgE total %
Synonyms
Cucumber IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens like pollen, dust mites, or certain foods. While IgE is normal in small amounts, higher levels may suggest allergies, asthma, or other immune-related conditions.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, skin rashes, or breathing difficulties that could be linked to allergies. It can also help diagnose conditions like allergic rhinitis, eczema, or certain types of asthma.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab, where it is analyzed to measure IgE levels using an immunoassay method. This test does not require fasting.

What Are Possible Results?

Results are reported in units per milliliter (U/mL) or international units per milliliter (IU/mL). Higher than normal IgE levels may indicate an allergic reaction or immune sensitivity, but interpretation depends on your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

How often do IgE levels change over time?
IgE levels can fluctuate depending on exposure to allergens, immune responses, or underlying health conditions. If you’ve had recent changes in symptoms, discuss this with your doctor before retesting.
What does it mean if my IgE level is very high?
Very high IgE levels often signal an allergic reaction or hypersensitivity. Your doctor may recommend further testing, like skin prick tests or allergy-specific IgE tests, to identify triggers.
Can diet affect IgE test results?
Diet does not typically affect IgE test results, but avoiding known allergens before testing may help clarify results if symptoms are present.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy