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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to a protein in your blood, often used to assess liver function or protein synthesis.

Quick summary

["This test helps check liver health or protein levels in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6236-4
Short code
Cultivated Rye IgE Qn
Synonyms
Cultivated Rye IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Bromocresol green (BCG) is a dye that binds to albumin, a key protein produced by your liver. When this dye binds, it changes color, which helps doctors measure how much protein is available in your blood. This test can indirectly reflect liver function or protein synthesis capacity.

Why It Might Be Ordered

Your doctor may order this test if they suspect liver disease, protein disorders, or other conditions affecting protein production. It’s sometimes used alongside other tests to get a clearer picture of liver health or nutritional status.

Common Conditions Monitored

While less commonly used today, BCG dye binding tests historically helped diagnose conditions like liver cirrhosis, malnutrition, or protein-losing syndromes. Modern tests often replace it with more direct protein measurements.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The sample is sent to a lab where it’s tested for how much bromocresol green binds to proteins. Results are reported as a ratio or percentage of dye binding compared to a standard.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

BCG Dye Binding Test

Frequently asked questions

This test is primarily historical but may still appear in older medical records or specific clinical contexts. It provides indirect insight into liver function and protein metabolism, though newer tests like albumin or globulin levels are preferred for diagnosis.
This test may not be widely available today and is often replaced by simpler, more direct protein or liver function tests. Always confirm with your healthcare provider if this test is being used for your care.
How long will it take to get results?
Results from this test typically arrive within 1–3 business days, depending on lab processing times. Your doctor will discuss the results with you during your follow-up visit.
What does a low or high result mean?
A low BCG dye binding result may suggest reduced protein levels or liver dysfunction, while a high result could indicate normal protein synthesis. Since this test is less common, your doctor will interpret results in the context of your overall health and other tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy