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Bromocresol Green Protein Electrophoresis (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures protein distribution in your blood using electrophoresis with the bromocresol green dye, helping assess conditions affecting protein balance.

Quick summary

["This test helps diagnose and monitor protein disorders by showing how proteins separate in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56381-7
Short code
Cultivated Rye IgG4-mCnc
Synonyms
Cultivated Rye IgG4-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The bromocresol green dye binds to different protein fractions in your blood, allowing them to separate based on size and charge during electrophoresis. This creates a pattern that reflects the types and amounts of proteins present, including albumin and globulins.

Why It’s Done

Your healthcare provider may order this test to evaluate conditions like hypoalbuminemia (low albumin), protein-losing syndromes, or certain types of liver or kidney disease that alter protein levels.

Sample Preparation

A blood sample is drawn, typically from a vein in your arm. The serum or plasma is then processed for electrophoresis, where an electric field separates proteins for analysis.

Common Conditions Monitored

This test helps identify imbalances in protein fractions that may indicate systemic issues like inflammation, chronic disease, or metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Abnormal protein patterns can signal underlying health issues, such as liver dysfunction, kidney disease, or immune system disorders. Low albumin may indicate malnutrition or fluid retention, while altered globulin levels could reflect immune responses or organ damage.

Short name

BCG Protein Electrophoresis

Frequently asked questions

What does a normal result mean?
A normal result suggests balanced protein levels in your blood, with typical distribution patterns for albumin and globulins. However, individual results can vary based on age, health status, and other factors.
How often should I get this test?
Your doctor will determine the frequency based on your medical history, symptoms, and treatment needs. Follow-up tests may be scheduled if you have ongoing conditions affecting proteins.
Can diet affect this test result?
Yes, certain diets (e.g., high-protein or low-protein) or medical conditions (e.g., kidney disease) may influence protein levels. Always discuss your diet and health with your provider before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy