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Total Bilirubin (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice or bile duct blockages.

Quick summary

["Bilirubin helps identify liver or bile issues and how well your body processes waste products."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94706-9
Short code
CV2 IgG Titr CSF IF
Synonyms
CV2 IgG Titr CSF IF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82977
SNOMED
3110003
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Matters

Bilirubin is a byproduct of hemoglobin breakdown, which occurs naturally in your body. High levels can signal problems with your liver, gallbladder, or bile ducts. Low levels may indicate certain blood disorders or liver disease progression.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually takes a few minutes. If you’re on blood thinners, let your provider know before the test.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions like jaundice (yellowing of skin/eyes), liver diseases (e.g., hepatitis), bile duct obstructions, or hemolytic anemia (red blood cell destruction). It can also help track treatment progress.

What Results Mean

Results are typically reported in milligrams per deciliter (mg/dL). Elevated levels may indicate liver or bile issues, while very low levels could suggest certain blood disorders. Your doctor will interpret results in the context of your overall health.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: csf

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Bilirubin Level

Frequently asked questions

How often do I need this test?
The frequency depends on your health condition. If you have liver disease or jaundice, your doctor may order this test regularly. Otherwise, it’s often done as needed for symptoms or routine checkups.
Can diet affect bilirubin levels?
Dietary changes rarely affect bilirubin directly, but certain foods (e.g., high-fiber, cruciferous vegetables) may influence liver function indirectly. Always follow your doctor’s advice for dietary adjustments.
Is there any risk with this test?
Minimal risks include mild bruising, soreness, or a small blood clot at the injection site. Rarely, allergic reactions to the blood draw process can occur. Most side effects are mild and temporary.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy