Cva2abtitrcsf
This test detects antibodies against Coxsackievirus A2 in cerebrospinal fluid to help diagnose viral infections of the brain and spinal cord.
{"Detects antibodies to Coxsackievirus A2 in brain fluid","Helps diagnose viral meningitis or encephalitis","Sample is collected via lumbar puncture (spinal tap)","Results help guide appropriate treatment","Often ordered with other viral tests for complete diagnosis"}
Key facts at a glance
- LOINC
- 16682-7
- Short code
- COXA2 CSF Titer
- Synonyms
- CV A2 Ab Titr CSF
- Category
- cardiac
- Sample
- csf
- Container
- Sterile plastic or glass tube for CSF collection (typically 12 x 75 mm polystyrene or polypropylene tube); avoid glass tubes that may adsorb proteins
- Units
- N/A
- Ref low
- 0
- Ref high
- 1
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Enzyme Immunoassay (EIA/ELISA) or Immunofluorescence Assay (IFA) for detection of Coxsackievirus A2-specific IgG and/or IgM antibodies in cerebrospinal fluid
- CPT
- 86658
- SNOMED
- 122449006
- Specimen volume
- 1-2 mL of cerebrospinal fluid; minimum 0.5 mL for testing
- Stability
- Specimen should be transported to laboratory immediately. Store at 2-8°C if testing within 24-48 hours. For prolonged storage, freeze at -70°C or below. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What is this test?
The Coxsackievirus A2 antibody test measures the presence and quantity of antibodies against Coxsackievirus A2 in your cerebrospinal fluid (CSF). CSF is the clear fluid that surrounds your brain and spinal cord. This test helps doctors determine if your nervous system infection is caused by this specific virus.
How is the sample collected?
The CSF sample is collected through a procedure called a lumbar puncture, also known as a spinal tap. A healthcare provider inserts a thin needle into the lower back to withdraw cerebrospinal fluid. This procedure is performed by trained medical professionals and usually takes about 15-30 minutes.
Why is this test ordered?
Your doctor may order this test if you have symptoms of a brain or spinal cord infection, such as fever, severe headache, stiff neck, confusion, or sensitivity to light. Coxsackievirus A2 is a type of enterovirus that can cause viral meningitis, encephalitis, or other neurological complications.
Reference range
Negative or <1:8 titer; Specific interpretive criteria vary by laboratory methodology. Positive results indicate intrathecal production of Coxsackievirus A2 antibodies suggesting central nervous system infection.N/A
No fasting required. Patient should be informed about the lumbar puncture procedure. Adequate hydration is recommended. Consent should be obtained. Contraindications include increased intracranial pressure, skin infection at puncture site, and coagulopathy.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Is the lumbar puncture procedure painful?
How long does it take to get results?
What do the results mean?
Is this test related to heart conditions?
Sources
- 1CDC - EnterovirusesSource
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy