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Cva7abtitrfldcf

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies against Coxsackievirus A7 in body fluids, helping diagnose viral infections that may affect the heart.

Quick summary

{"Coxsackievirus A7 is a virus that can cause heart inflammation (myocarditis)","The test uses complement fixation to detect antibodies your body makes against the virus","Results help doctors determine if a recent or past viral infection is affecting your heart","A positive result indicates past or current infection with this specific virus type","The test is performed on serum (blood) or other body fluids"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31049-0
Short code
COXA7
Synonyms
CV A7 Ab Titr Fld CF
Category
cardiac
Sample
serum
Container
Serum separator tube (SST) or red top tube
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
comp-fix
CPT
86658
SNOMED
122441004
Specimen volume
1-2 mL of serum
Stability
Refrigerated (2-8°C) for up to 7 days; frozen (-20°C or lower) for longer storage up to 3 months
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
48–168 hours
Order
routine

What is this test?

The Coxsackievirus A7 Antibody test is a laboratory test that detects the presence of antibodies specifically directed against Coxsackievirus A7, a type of enterovirus. The test uses a method called complement fixation, which is a technique that identifies whether your immune system has produced specific antibodies in response to a Coxsackievirus A7 infection. This test is primarily ordered to help diagnose viral infections that may be affecting the heart, particularly myocarditis (inflammation of the heart muscle).

Why might I need this test?

Your doctor may order this test if you have symptoms of a viral infection affecting your heart, such as chest pain, shortness of breath, irregular heartbeat, fatigue, or flu-like symptoms that persist. It is particularly useful when other common causes of heart inflammation have been ruled out. The test helps distinguish between current (recent) and past infections by measuring antibody levels (titers).

How is the test performed?

A healthcare professional will collect a sample of your blood (serum) from a vein in your arm, or occasionally from other body fluids depending on your symptoms. The sample is then sent to a laboratory where technicians use the complement fixation method to detect and measure the levels of Coxsackievirus A7-specific antibodies. This technique involves mixing the patient serum with known viral antigens and complement proteins to see if an immune reaction occurs.

What do the results mean?

A positive result indicates that antibodies to Coxsackievirus A7 were detected in your sample, suggesting you have been infected with this virus at some point. A high titer (concentration) of antibodies typically indicates a recent or current infection. A negative result means no antibodies were detected, which could mean you have not been infected with Coxsackievirus A7, or the infection was in the very early stages before antibodies developed. Your doctor will interpret these results in conjunction with your symptoms and other test findings.

Reference range

Negative: <1:8; Equivocal: 1:8; Positive: >1:8. A four-fold rise in titer between acute and convalescent specimens indicates recent infection.N/A

Specimen: serum

No special preparation required. Standard venipuncture procedure. Inform laboratory of recent infections or immunizations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is this test painful?
The test involves a standard blood draw, which may cause brief discomfort or a minor sting when the needle is inserted. The procedure typically takes only a few minutes.
Do I need to fast before this test?
Fasting is usually not required for this test. However, follow any specific instructions provided by your healthcare provider.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the laboratory. Your healthcare provider will contact you with the results.
Can this test distinguish between current and past infections?
Yes, the complement fixation test can help differentiate between recent and past infections by measuring antibody levels (titers). A four-fold increase in antibody levels between acute and convalescent samples typically indicates a recent infection.
Is Coxsackievirus A7 the same as hand, foot, and mouth disease?
Coxsackievirus A7 is one of several viruses that can cause hand, foot, and mouth disease, but it is also associated with more serious conditions like myocarditis. The test specifically looks for antibodies to this particular strain.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy