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Published: August 9, 2026Updated: August 17, 2026

This blood test detects IgG antibodies against Coxsackievirus A7, a virus that can cause hand, foot and mouth disease and occasionally heart complications.

Quick summary

{"Measures IgG antibodies indicating past or recent Coxsackievirus A7 infection","Uses immunofluorescence technique on blood sample","Used to help diagnose viral causes of heart inflammation","Results are reported as antibody titers (levels)"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
59584-3
Short code
COXA7IGG
Synonyms
CV A7 IgG Titr Ser IF
Category
cardiac
Sample
serum
Container
Serum separator tube (SST) or plain red top tube
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunofluorescence (IFA)
CPT
86658
SNOMED
371949004
Specimen volume
1.0 mL minimum, 2.0 mL preferred
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
72–168 hours
Order
routine

What is this test?

The Coxsackievirus A7 IgG Antibody Test is a blood test that detects IgG antibodies your body produces in response to Coxsackievirus A7 infection. This virus belongs to the enterovirus family and is known to cause hand, foot and mouth disease, particularly in children. The test uses a method called immunofluorescence to detect and measure the level of antibodies in your blood.

How is the test performed?

A healthcare professional will collect a blood sample from a vein in your arm. This sample is then sent to a laboratory where technicians use immunofluorescence techniques to detect and measure IgG antibodies specific to Coxsackievirus A7. The results are typically reported as a titer, which indicates the concentration of antibodies in your blood.

Why might I need this test?

Your doctor may order this test if you have symptoms of a recent viral infection, particularly if you have symptoms affecting the heart such as chest pain, shortness of breath, or abnormal heart rhythms. It may also be ordered if you have a history of hand, foot and mouth disease and are experiencing cardiac symptoms. The test helps determine if a Coxsackievirus A7 infection may be related to your current health condition.

What do the results mean?

A positive IgG result indicates that you have been infected with Coxsackievirus A7 at some point, as IgG antibodies develop after infection and typically remain in the body for a long time. The titer level can help determine if the infection is recent or past. Your doctor will interpret these results in combination with your symptoms, physical examination, and other test results to make a diagnosis.

Reference range

NCBI: GGT Male 8-61 U/L; Female 5-36 U/LN/A

Specimen: serum

No special preparation required. Standard venipuncture precautions apply. Inform laboratory of recent infections or immunizations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
No, you do not need to fast before this test. You can eat and drink normally before having your blood drawn.
How long does it take to get results?
Results typically take 2-5 days, depending on the laboratory. Your healthcare provider will contact you with the results or discuss them at your follow-up appointment.
What is the difference between IgG and IgM antibodies?
IgM antibodies appear first during an infection and indicate a recent or current infection. IgG antibodies develop later and typically remain in the body for years, providing long-term immunity. This test specifically looks for IgG antibodies, which can indicate either a past or recent infection when interpreted with clinical context.
Is this test contagious?
No, this test only detects antibodies in your blood. It does not involve testing for live virus and cannot transmit any infection.
What should I tell my doctor before the test?
Inform your doctor about any recent illnesses, especially viral infections, any medications you are taking, and if you have a known history of heart conditions. Also let them know if you have ever been diagnosed with hand, foot and mouth disease.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy