Cvb5absp2titrser
This blood test measures antibodies against Coxsackievirus B5, a virus that can cause heart inflammation. The second specimen helps doctors see if your immune response is changing over time.
{"Measures immune response to Coxsackievirus B5 infection","Helps diagnose virus-related heart conditions like myocarditis","Comparing two blood samples shows if infection is recent or past","No special preparation is needed for this blood test","Results help your doctor understand what may be causing heart symptoms"}
Key facts at a glance
- LOINC
- 24268-5
- Short code
- CVB5
- Synonyms
- CV B5 Ab sp2 Titr Ser
- Category
- cardiac
- Sample
- serum
- Container
- SST (Serum Separator Tube) or Red Top Tube
- Units
- N/A
- Ref low
- 0
- Ref high
- 1
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Complement Fixation (CF) or Neutralization Assay
- CPT
- 86658
- SNOMED
- 371949004
- Specimen volume
- 1.0-2.0 mL serum minimum
- Stability
- Refrigerated (2-8°C) for up to 7 days; Frozen (-20°C or below) for several weeks to months; Avoid repeated freeze-thaw cycles
- Hemolysis max
- 50
- Lipemia max
- 100
- Icterus max
- 20
- TAT
- 48–168 hours
- Order
- routine
What is this test?
The Coxsackievirus B5 antibody test is a blood test that looks for specific antibodies—your body's immune system proteins—that fight against Coxsackievirus B5. This virus is part of a group of viruses that commonly infect humans and can sometimes lead to heart problems. When you have a second specimen taken, doctors can compare antibody levels from two different times to understand if you have a current, recent, or past infection.
Why might I need this test?
Your doctor may order this test if you have symptoms that could be related to heart inflammation, such as chest pain, shortness of breath, fatigue, or irregular heartbeat. Coxsackievirus B5 is one of the viruses known to cause myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the sac around the heart). This test helps your doctor determine if a viral infection might be the cause of your heart symptoms.
What happens during the test?
A healthcare professional will take a blood sample from a vein in your arm, similar to other routine blood tests. You may feel a brief sting or pinch when the needle is inserted. The sample is then sent to a laboratory where technicians look for antibodies specifically targeting Coxsackievirus B5. Since this is a 'second specimen' test, you will likely need to give two blood samples—usually taken several weeks apart—to see how your antibody levels have changed.
What do the results mean?
The results show whether you have antibodies against Coxsackievirus B5 and how much you have. A rising level of antibodies between your first and second blood samples suggests a recent or active infection. Stable or decreasing levels may indicate a past infection. Your doctor will interpret these results together with your symptoms, physical exam, and other test results to determine the best course of treatment, if needed.
Reference range
Negative or <1:8 titer indicates no evidence of recent infection; ≥1:160 titer suggests recent or acute Coxsackievirus B5 infection; Four-fold rise in titer between acute and convalescent specimens indicates recent infectionN/A
No special preparation required. This is the second specimen collected 2-4 weeks after the acute specimen for paired testing to demonstrate seroconversion or rising antibody titers
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Do I need to fast before this test?
How long does it take to get results?
What if my test is positive?
Is this test dangerous?
Can this test tell me if I have COVID-19 or other respiratory viruses?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 14, 2026. · Read our editorial policy