Creatinine Clearance (from 24-hour urine collection)
This test measures how well your kidneys filter waste products, specifically creatinine, over a full day. It helps assess kidney function and blood flow to the kidneys.
["This test helps doctors check how well your kidneys are working and if blood is flowing properly to them."]
Key facts at a glance
- LOINC
- 95639-1
- Short code
- CVV NAb Titr Spec Nt
- Synonyms
- CVV NAb Titr Spec Nt
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- neut
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Creatinine clearance is a key indicator of kidney function. Unlike a single blood test, this 24-hour urine test provides a more accurate picture of how efficiently your kidneys remove waste from your blood over time.
What to Expect Before the Test
You’ll collect all your urine for a full 24-hour period in a special container. Drink plenty of water to help your kidneys produce urine consistently. Avoid certain medications that might affect kidney function unless your doctor advises otherwise.
How the Test Works
Your urine sample is tested for creatinine levels, and your blood is typically measured for creatinine as well. The test calculates how much creatinine your body filters through your kidneys over 24 hours.
What the Results Mean
Results are usually reported as a clearance rate (e.g., mL/min). Lower than expected values may indicate kidney damage or poor blood flow, while higher values could suggest overhydration or other conditions. Your doctor will interpret these results in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
24-Hour Urine Creatinine Clearance
Frequently asked questions
What causes kidney function to change?
How often should I get this test?
Can I drink alcohol before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy