Chemokine (CXC motif) ligand 3, serum/plasma concentration
This test measures the amount of CXCL3, a protein involved in attracting immune cells to sites of inflammation or infection in your blood.
["CXCL3 helps your body respond to infections or tissue damage by signaling immune cells to the affected area."]
Key facts at a glance
- LOINC
- 107481-4
- Short code
- CX3CL1 CSF-mCnc
- Synonyms
- CX3CL1 CSF-mCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What Is CXCL3 Used For?
CXCL3 is primarily measured to assess immune system activity, particularly in conditions where inflammation or immune responses are suspected. It may be part of a broader panel to evaluate chronic inflammatory diseases, autoimmune conditions, or infections.
How Is the Test Performed?
A blood sample is drawn from a vein, typically in your arm. The sample is then processed to separate serum or plasma, where the CXCL3 protein is measured using a sensitive immunoassay technique.
When Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like persistent fever, unexplained weight loss, or signs of chronic inflammation. It could also be used in research or specialized clinical settings to monitor immune responses.
What Does a Result Mean?
Results are not typically interpreted alone but in the context of your symptoms and overall health. Elevated levels may suggest active inflammation or immune activity, while lower levels might indicate reduced immune response.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: CXCL3 plays a role in recruiting neutrophils and other immune cells to sites of infection or injury. Elevated levels can be associated with conditions such as certain infections, autoimmune diseases, or inflammatory disorders. However, its clinical utility is often limited to research or specialized diagnostic scenarios.
Short name
CXCL3 (Chemokine Ligand 3)
Frequently asked questions
Why would my doctor order this test?
What are the common reference ranges for this test?
Is there any preparation needed before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy