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Cytoplasmic Neutrophil Antigen-Related Lipocalin (NGAL) in Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called NGAL, which is found in white blood cells and can help assess kidney function or injury.

Quick summary

["NGAL helps monitor kidney health and response to illness or treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90743-6
Short code
CYBB full + NCF1 c.75_76delGT Bld/T
Synonyms
CYBB full + NCF1 c.75_76delGT Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms of kidney problems, such as swelling, fatigue, or changes in urine output. It can also be used to check how well your kidneys are recovering after an illness or injury, like a kidney infection or severe dehydration.

What Does the Test Involve?

A small blood sample is taken from a vein in your arm. The blood is then analyzed to measure NGAL levels. This test is typically done in a lab using a sensitive detection method to measure protein concentration.

What Do Results Mean?

Elevated NGAL levels may indicate kidney stress or damage, especially in conditions like acute kidney injury or certain infections. However, results can vary based on your overall health and medical history. Your doctor will interpret the results in the context of your symptoms and other tests.

What Are Possible Causes of Abnormal Results?

High NGAL levels can be caused by kidney problems, infections, heart failure, or severe dehydration. Low levels might not indicate a specific condition but could be part of normal variation depending on the individual’s health status.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: NGAL in Kidney Health Monitoring

Short name

NGAL Blood Test

Frequently asked questions

What does a high NGAL level mean for my health?
A high NGAL level may signal that your kidneys are under stress, which could be due to conditions like kidney disease, infection, or other systemic illnesses. Your doctor will discuss this with you and may recommend further tests or adjustments to your treatment plan.
Can NGAL levels change with diet or medications?
NGAL levels can be influenced by certain medications, especially those affecting kidney function or fluid balance. Dietary changes, such as reducing salt intake, might also indirectly affect kidney health but do not directly impact NGAL levels. Always follow your doctor’s advice regarding medications and diet.
Is this test painful?
The blood draw for this test is generally mild discomfort for a few minutes. Most people experience only a slight pinch or pressure. Afterward, you may have a small bruise or swelling at the site, but this usually goes away quickly.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy