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Cytoplasmic CD2 (cyCD2) Expression on Blasts — Flow Cytometry, Specimen

Published: August 9, 2026Updated: August 17, 2026

A flow cytometry test that detects cytoplasmic CD2 on blast cells to help characterize leukemia or lymphoma.

Quick summary

["This test shows whether abnormal blast cells carry the CD2 marker, which can help classify certain blood cancers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
51109-7
Short code
cyCD2 Blasts/Blasts NFr Spec
Synonyms
cyCD2 Blasts/Blasts NFr Spec
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures CD2, a protein found on the surface of some immune cells, within blast cells. Blasts are immature cells that may be found in blood or bone marrow when a blood cancer is suspected.

Why might I need this test?

A clinician may order this test as part of an immune-phenotyping panel to help identify the cell type of leukemia or lymphoma. CD2 is especially useful when evaluating certain T-cell and natural killer cell disorders.

How is the test performed?

The laboratory uses flow cytometry to examine cells from the submitted specimen, commonly blood or bone marrow. Fluorescent markers detect CD2, and the report may describe the proportion of blasts expressing it and the strength of the staining.

How do I prepare for the test?

A blood or bone marrow specimen is collected using the process specified by your clinician. No medication or food restrictions are generally required for this test, but follow the laboratory's collection instructions.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CD2 on blasts

Frequently asked questions

What does a positive CD2 result mean?
It means that the blast cells tested were found to carry the CD2 marker. This is one piece of information used to classify abnormal cells, not a diagnosis by itself.
What specimen is used for this test?
The specimen is usually peripheral blood or bone marrow. Your clinician or the laboratory will confirm the required sample.
Does this test diagnose leukemia or lymphoma?
No. It is usually one part of a larger evaluation that may include other flow cytometry markers, examination of blood or marrow cells, genetic testing, and clinical findings.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy