Skip to content

Cyclosporine Concentration (24-Hour Urine Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection after a transplant, in your urine over a 24-hour period. It helps doctors check if your dose is working properly.

Quick summary

["This test helps ensure your cyclosporine levels are safe and effective for your transplant care."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3523-8
Short code
cycloSPORINE 12h p Bld-mCnc
Synonyms
cycloSPORINE 12h p Bld-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking cyclosporine to manage organ rejection after a transplant. It helps track how well your body is processing the medication through urine, which can vary based on diet, hydration, and other factors.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, starting after you wake up the next morning. Store the urine in a clean container and keep it refrigerated until you return it to the lab. Follow your doctor’s instructions carefully to ensure accurate results.

How the Test Works

The collected urine sample is analyzed to measure cyclosporine levels. This test helps assess whether your medication is being eliminated from your body as expected, which can affect your dose.

What the Results Mean

Results help your healthcare team adjust your cyclosporine dose if needed. High levels may indicate the medication isn’t being processed properly, while low levels might suggest you need more. Your doctor will interpret the results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Urine Cyclosporine

Frequently asked questions

How often should I get this test?
Your doctor will determine the timing and frequency based on your transplant care plan, typically every few weeks or months. Follow their guidance to ensure optimal monitoring.
Can I drink alcohol before this test?
Alcohol may affect urine concentration and could influence results. Ask your doctor or lab staff about any restrictions before your test.
What if I miss a urine collection period?
If you miss any urine, you’ll need to restart the 24-hour collection. Contact your doctor or lab immediately to reschedule if needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy