24-Hour Urine Cyclosporine Concentration (Mass)
This test measures the total amount of cyclosporine excreted in your urine over a 24-hour period. Cyclosporine is a medication used to suppress the immune system, often prescribed for conditions like organ transplants or autoimmune diseases.
["This test helps monitor how well your body is processing cyclosporine through urine, ensuring safe and effective dosing."]
Key facts at a glance
- LOINC
- 3526-1
- Short code
- cycloSPORINE 24h p Ser-mCnc
- Synonyms
- cycloSPORINE 24h p Ser-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 20
- Ref high
- 400
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82670
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you’re taking cyclosporine to check how your kidneys are handling the medication. It helps adjust your dose to prevent side effects like high blood pressure, kidney damage, or low white blood cell counts.
What to Expect Before the Test
No special preparation is needed. You’ll collect all urine for 24 hours in a container provided by your lab. Drink plenty of fluids to help your kidneys pass the medication naturally.
How the Test Works
The collected urine sample is analyzed in a lab using a sensitive method (likely liquid chromatography or immunoassay) to measure cyclosporine levels. This helps track how much of the drug is being eliminated.
What the Results Mean
Results are typically reported as the total mass of cyclosporine excreted in milligrams (mg) over 24 hours. High or low levels may signal issues with drug metabolism or kidney function.
Reference range
Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal results can indicate whether your dose is too high (risking toxicity) or too low (risking insufficient immune suppression). This test is critical for patients on long-term cyclosporine therapy to balance safety and effectiveness.
Short name
24h Urine Cyclosporine
Frequently asked questions
Why do I need this test?
How often will I need this test?
What if my results are out of range?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy