Skip to content

Cyclosporine concentration in whole blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection after transplant or to suppress immune responses in certain conditions, in your blood.

Quick summary

["This helps doctors monitor your dose to balance effectiveness and side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32997-9
Short code
cycloSPORINE 2h p Bld-mCnc
Synonyms
cycloSPORINE 2h p Bld-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82670
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’re taking cyclosporine to ensure your dose stays within safe levels. It helps prevent your body from rejecting a transplanted organ or managing immune-related conditions like rheumatoid arthritis or psoriasis.

What to Expect Before the Test

No special preparation is needed. A healthcare professional will draw blood from a vein in your arm. The process takes about 5 minutes, and you may feel a slight pinch or discomfort.

What the Results Mean

Results help your doctor determine if your cyclosporine level is too high or too low. High levels may cause side effects like kidney problems or increased infection risk, while low levels might mean the medication isn’t working as intended.

Common Side Effects of Cyclosporine

Cyclosporine can cause side effects like kidney issues, high blood pressure, or increased risk of infections. Your doctor will adjust your dose based on these test results to minimize risks.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cyclosporine blood levels are critical for transplant patients and those with immune-suppressing conditions. Too much can harm organs or weaken immunity, while too little may reduce the medication’s effectiveness. Regular monitoring ensures safety and treatment success.

Short name

Cyclosporine Blood Level

Frequently asked questions

Why do I need this test regularly?
Regular testing helps your doctor keep your cyclosporine levels stable, preventing both underdosing (which may not work well) and overdosing (which can cause serious side effects).
What happens if my cyclosporine level is too high?
If levels are too high, your doctor may lower your dose or temporarily stop the medication to reduce risks like kidney damage or infections. They’ll retest until the level is safe.
Can I eat or drink before this test?
You can eat and drink normally before the test, as no fasting is required. However, always follow your doctor’s specific instructions for your situation.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy