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Cyclosporine concentration (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection or suppress immune responses, in your blood.

Quick summary

["Your cyclosporine level helps doctors monitor your dose and ensure it stays within safe ranges."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77168-3
Short code
cycloSPORINE 4h p Bld-mCnc
Synonyms
cycloSPORINE 4h p Bld-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors order cyclosporine blood tests to check if your medication is working properly. It’s especially important if you’re taking this drug to prevent rejection after an organ transplant or manage conditions like severe rheumatoid arthritis or psoriasis. Regular testing helps avoid side effects, such as high blood pressure or kidney problems, by adjusting your dose as needed.

How the Test Works

Blood is drawn from a vein, usually in your arm. The sample is then tested using a sensitive method (likely immunoassay or chromatography) to measure cyclosporine levels in your serum or plasma.

What to Expect Before the Test

There are no special preparations needed for this test. You may have some mild discomfort from the needle, but it’s a quick process. If you’re on cyclosporine, your doctor will likely schedule tests at regular intervals to track your levels.

Possible Results and Next Steps

Results are compared to your doctor’s target range, which depends on your condition and how your body processes the drug. If levels are too high or too low, your doctor may adjust your dose or recommend lifestyle changes (like diet or supplements) to help manage it.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Cyclosporine Level

Frequently asked questions

What does a high cyclosporine level mean?
High levels may indicate your body isn’t breaking down the drug properly, which can lead to side effects like kidney damage, high blood pressure, or infections. Your doctor may reduce your dose or switch to a different medication.
What does a low cyclosporine level mean?
Low levels might mean your body is metabolizing the drug too quickly, which could increase your risk of organ rejection or flare-ups of your condition. Your doctor may increase your dose or check for interactions with other medications.
How often should I get this test?
Your doctor will determine the timing based on your treatment plan, but it’s often done weekly or monthly during active therapy to ensure safe dosing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy